Unzipping and binding of small interfering RNA with single walled carbon nanotube: A platform for small interfering RNA delivery
نویسندگان
چکیده
منابع مشابه
Unzipping and binding of small interfering RNA with single walled carbon nanotube: a platform for small interfering RNA delivery.
In an effort to design efficient platform for siRNA delivery, we combine all atom classical and quantum simulations to study the binding of small interfering RNA (siRNA) by pristine single wall carbon nanotube (SWCNT). Our results show that siRNA strongly binds to SWCNT surface via unzipping its base-pairs and the propensity of unzipping increases with the increase in the diameter of the SWCNTs...
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ژورنال
عنوان ژورنال: The Journal of Chemical Physics
سال: 2012
ISSN: 0021-9606,1089-7690
DOI: 10.1063/1.3682780